Present a Clinical Case of Perioperative Anaphylaxis Share patient background, surgical context, anesthetic plan, and intraoperative events leading to anaphylaxis. Describe the Clinical Features and Diagnosis of Anaphylaxis Highlight signs, symptoms, and diagnostic criteria including grading systems and biomarkers. Review the Pathophysiology of Anaphylactic and Anaphylactoid Reactions Explain immune-mediated and non-immune mechanisms, including the role of IgE, mast cells, and mediators. Identify Common Triggers in the Perioperative Setting Discuss causative agents such as neuromuscular blockers, antibiotics, latex, and colloids. Outline Emergency Management Protocols Detail immediate interventions including airway support, adrenaline administration, fluid resuscitation, and adjunct therapies. Discuss Investigations and Post-Event Evaluation Recommend appropriate lab tests (e.g., tryptase, histamine levels) and imaging to assess organ perfusion and injury. Explore Strategies for Prevention and Risk Reduction Emphasize allergen identification, documentation, and use of skin testing post-event. Reflect on Key Learning Points from the Case Analyze what went well, areas for improvement, and system-level considerations for future preparedness. Promote Evidence-Based Practice and Team Coordination Encourage use of guidelines, quick reference tools, and multidisciplinary collaboration in managing perioperative emergencies.