By the end of the discussion, participants should be able to: Explain hantavirus and its significance as a rodent-borne zoonotic infection. Describe the modes of transmission of hantavirus from rodents to humans. Discuss the pathogenesis of hantavirus infection, particularly endothelial injury and increased vascular permeability. Identify the major clinical manifestations and syndromes associated with hantavirus infection. Describe the laboratory findings and diagnostic approaches used to identify hantavirus infection. Outline the principles of treatment and supportive clinical management of hantavirus infection. Explain preventive measures, including environmental sanitation, rodent control, and reduction of human exposure to infected rodents. Discuss the importance of recognizing zoonotic spillover risks in protecting human health.