Starting on:
Aug 14, 2024
Ending on:
Aug 14, 2024
Moderator(s):
Venue:
kutrrh
Max Credits:
3 Points
Provider:
Kenyatta University Teaching and Referral Hospital
Claim Points
Aug 14, 2024
Ending on:
Aug 14, 2024
Moderator(s):
kutrrh
Max Credits:
3 Points
Provider:
Kenyatta University Teaching and Referral Hospital
Claim Points
Neonatal Seizures
Starting on:
Aug 14, 2024
Aug 14, 2024
Ending on:
Aug 14, 2024
Aug 14, 2024
Venue:
kutrrh
kutrrh
Description
Neonatal seizures refer to seizures occurring within the first 28days of life for term babies and gestational age of 44days for preterms Children are at the highest risk of seizures during their first month of life Seizures are the first sign of neurological dysfunction in neonates It is crucial to determine the underlying etiology promptly to prevent poor outcomes such as long-term cognitive development and impairment
Objectives
Seizures occur when a large group of neurons undergo excessive, synchronized depolarization. Depolarization can result from excessive excitatory amino acid release (eg, glutamate) or deficient inhibitory neurotransmitter (eg, gamma amino butyric acid [GABA]).
The biochemical effects of neonatal seizures include derangements of energy metabolism. Energy-dependent ion pumps are compromised, and adenosine diphosphate (ADP) levels rise. The rise in ADP stimulates glycolysis with the ultimate increase in pyruvate, which accumulates as a result of compromised mitochondrial function.
Presenters
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Dr.
Dr. Ann Kamunya
dr
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Dr.
Dr Kendi Tiffany
Dr